Experiment ID: 2574

Field Description
namecaloric restriction disrupts the microbiota and colonization resistance (8959578) - gpt-5
proj_id8959578
sraprjna412411
date_of_upload17/03/2026 19:45
doi10.1038/s41586-021-03663-4
modelgpt-5
sample_groups_version18
dbbact_id814
dbbact_linkhttps://dbbact.org/exp_info/814
needs_manual_reviewtrue

Annotations for experiment:

Fraction of annotations for the query sequences containing the term
TermScore
feces1.000000
morbid obesity0.500000
clinical research center0.500000
human adult stage0.500000
obesity0.500000
homo sapiens0.500000
overweight body mass index status0.500000
postmenopausal0.500000
female organism0.500000
germany0.500000
berlin0.500000
united states of america0.500000
male organism0.500000
mus musculus0.500000
san francisco0.500000
humanized microbiota0.500000
c57bl/6j0.500000
gnotobiotic facility0.500000
germ-free0.500000
weight loss diet0.277778
very low-calorie diet0.277778
pre-diet microbiota0.277778
c. difficile carriage0.222222
post-diet microbiota0.222222
weight maintenance0.222222
control0.222222
LOWER IN united states of america0.166667
LOWER IN male organism0.166667
LOWER IN mus musculus0.166667
LOWER IN san francisco0.166667
LOWER IN humanized microbiota0.166667
LOWER IN c57bl/6j0.166667
LOWER IN gnotobiotic facility0.166667
LOWER IN germ-free0.166667
LOWER IN morbid obesity0.166667
LOWER IN clinical research center0.166667
LOWER IN human adult stage0.166667
LOWER IN obesity0.166667
LOWER IN homo sapiens0.166667
LOWER IN weight loss diet0.166667
LOWER IN overweight body mass index status0.166667
LOWER IN very low-calorie diet0.166667
LOWER IN postmenopausal0.166667
LOWER IN female organism0.166667
LOWER IN germany0.166667
LOWER IN berlin0.166667
LOWER IN pre-diet microbiota0.166667
LOWER IN c. difficile carriage0.111111
LOWER IN post-diet microbiota0.111111
LOWER IN weight maintenance0.111111
LOWER IN control0.111111
Number of experiments associating the term to the sequence
TermScore
morbid obesity1.000000
clinical research center1.000000
human adult stage1.000000
obesity1.000000
homo sapiens1.000000
weight loss diet1.000000
overweight body mass index status1.000000
very low-calorie diet1.000000
postmenopausal1.000000
female organism1.000000
germany1.000000
berlin1.000000
LOWER IN united states of america1.000000
LOWER IN c. difficile carriage1.000000
LOWER IN male organism1.000000
LOWER IN mus musculus1.000000
LOWER IN post-diet microbiota1.000000
LOWER IN san francisco1.000000
LOWER IN humanized microbiota1.000000
LOWER IN c57bl/6j1.000000
LOWER IN gnotobiotic facility1.000000
LOWER IN germ-free1.000000
feces1.000000
united states of america1.000000
c. difficile carriage1.000000
male organism1.000000
mus musculus1.000000
post-diet microbiota1.000000
san francisco1.000000
humanized microbiota1.000000
c57bl/6j1.000000
gnotobiotic facility1.000000
germ-free1.000000
LOWER IN morbid obesity1.000000
LOWER IN clinical research center1.000000
LOWER IN human adult stage1.000000
LOWER IN obesity1.000000
LOWER IN homo sapiens1.000000
LOWER IN weight loss diet1.000000
LOWER IN overweight body mass index status1.000000
LOWER IN very low-calorie diet1.000000
LOWER IN postmenopausal1.000000
LOWER IN female organism1.000000
LOWER IN germany1.000000
LOWER IN berlin1.000000
pre-diet microbiota1.000000
LOWER IN weight maintenance1.000000
LOWER IN control1.000000
LOWER IN pre-diet microbiota1.000000
weight maintenance1.000000
control1.000000
Exp. ID User ID Description Date Region Sequences Status Flag
2574gpt-5Mouse fecal samples colonized with pre-diet human microbiota (dominant pre-diet microbiota, united states of america, feces, mus musculus, male organism, san francisco, humanized microbiota, c57bl/6j, gnotobiotic facility, germ-free)2026-03-17v41 / 18pendingNo
2574gpt-5Human fecal samples from diet intervention group (VLCD study) (dominant morbid obesity, clinical research center, human adult stage, obesity, feces, homo sapiens, female organism, weight loss diet, overweight body mass index status, very low-calorie diet, postmenopausal, germany, berlin)2026-03-17v41 / 22pendingNo
2574gpt-5Mouse fecal samples colonized with post-diet human microbiota (dominant united states of america, c. difficile carriage, feces, mus musculus, post-diet microbiota, san francisco, male organism, humanized microbiota, c57bl/6j, gnotobiotic facility, germ-free)2026-03-17v41 / 22pendingNo
2574gpt-5Human fecal samples from control group (weight-stable participants) (dominant morbid obesity, clinical research center, human adult stage, obesity, feces, homo sapiens, female organism, overweight body mass index status, weight maintenance, postmenopausal, germany, berlin, control)2026-03-17v41 / 23pendingNo
2574gpt-5Diet intervention vs weight-stable controls in human fecal microbiome ( high in control weight maintenance compared to weight loss diet very low-calorie diet in morbid obesity clinical research center human adult stage obesity feces homo sapiens overweight body mass index status postmenopausal female organism germany berlin )2026-03-17v41 / 27pendingNo
2574gpt-5Diet intervention vs weight-stable controls in human fecal microbiome ( high in weight loss diet very low-calorie diet compared to control weight maintenance in morbid obesity clinical research center human adult stage obesity feces homo sapiens overweight body mass index status postmenopausal female organism germany berlin )2026-03-17v41 / 36pendingNo
2574gpt-5Human fecal samples from control group (weight-stable participants) (common morbid obesity, clinical research center, human adult stage, obesity, feces, homo sapiens, female organism, overweight body mass index status, weight maintenance, postmenopausal, germany, berlin, control)2026-03-17v41 / 43pendingNo
2574gpt-5Human fecal samples from diet intervention group (VLCD study) (common morbid obesity, clinical research center, human adult stage, obesity, feces, homo sapiens, female organism, weight loss diet, overweight body mass index status, very low-calorie diet, postmenopausal, germany, berlin)2026-03-17v41 / 57pendingNo
2574gpt-5Impact of VLCD on transmissible microbiome features: mice colonized with post-diet vs pre-diet human microbiota ( high in post-diet microbiota c. difficile carriage compared to pre-diet microbiota in united states of america feces male organism mus musculus san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free )2026-03-17v41 / 82pendingNo
2574gpt-5Mouse fecal samples colonized with post-diet human microbiota (common united states of america, c. difficile carriage, feces, mus musculus, post-diet microbiota, san francisco, male organism, humanized microbiota, c57bl/6j, gnotobiotic facility, germ-free)2026-03-17v41 / 95pendingNo
2574gpt-5Baseline human microbiota vs corresponding pre-diet humanized mice (pre-intervention state) ( high in morbid obesity clinical research center human adult stage obesity homo sapiens overweight body mass index status weight maintenance postmenopausal female organism germany berlin control compared to pre-diet microbiota united states of america male organism mus musculus san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free in feces )2026-03-17v41 / 96pendingNo
2574gpt-5Mouse fecal samples colonized with pre-diet human microbiota (common pre-diet microbiota, united states of america, feces, mus musculus, male organism, san francisco, humanized microbiota, c57bl/6j, gnotobiotic facility, germ-free)2026-03-17v41 / 102pendingNo
2574gpt-5Diet effect across species contexts: human intervention group vs mice colonized with pre-diet microbiota ( high in morbid obesity clinical research center human adult stage obesity homo sapiens weight loss diet overweight body mass index status very low-calorie diet postmenopausal female organism germany berlin compared to pre-diet microbiota united states of america male organism mus musculus san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free in feces )2026-03-17v41 / 106pendingNo
2574gpt-5Impact of VLCD on transmissible microbiome features: mice colonized with post-diet vs pre-diet human microbiota ( high in pre-diet microbiota compared to post-diet microbiota c. difficile carriage in united states of america feces male organism mus musculus san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free )2026-03-17v41 / 108pendingNo
2574gpt-5Diet effect across species contexts: human intervention group vs mice colonized with pre-diet microbiota ( high in pre-diet microbiota united states of america male organism mus musculus san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free compared to morbid obesity clinical research center human adult stage obesity homo sapiens weight loss diet overweight body mass index status very low-calorie diet postmenopausal female organism germany berlin in feces )2026-03-17v41 / 172pendingNo
2574gpt-5Baseline human microbiota vs corresponding pre-diet humanized mice (pre-intervention state) ( high in pre-diet microbiota united states of america male organism mus musculus san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free compared to morbid obesity clinical research center human adult stage obesity homo sapiens overweight body mass index status weight maintenance postmenopausal female organism germany berlin control in feces )2026-03-17v41 / 179pendingNo
2574gpt-5Cross-species transfer: human diet-intervention signature recapitulated in gnotobiotic mice (post-diet donors) ( high in united states of america c. difficile carriage male organism mus musculus post-diet microbiota san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free compared to morbid obesity clinical research center human adult stage obesity homo sapiens weight loss diet overweight body mass index status very low-calorie diet postmenopausal female organism germany berlin in feces )2026-03-17v41 / 195pendingNo
2574gpt-5Cross-species transfer: human diet-intervention signature recapitulated in gnotobiotic mice (post-diet donors) ( high in morbid obesity clinical research center human adult stage obesity homo sapiens weight loss diet overweight body mass index status very low-calorie diet postmenopausal female organism germany berlin compared to united states of america c. difficile carriage male organism mus musculus post-diet microbiota san francisco humanized microbiota c57bl/6j gnotobiotic facility germ-free in feces )2026-03-17v41 / 197pendingNo

Problems / suggestions? Please visit the dbBact forum