Experiment ID: 2354

Field Description
namethe antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse (4266663) - gpt-5
proj_id4266663
sraprjna264871
date_of_upload05/03/2026 07:25
doi10.1371/journal.pone.0115225
modelgpt-5
sample_groups_version18
dbbact_id123
dbbact_linkhttps://dbbact.org/exp_info/123
needs_manual_reviewtrue

Annotations for experiment:

term enrichment score
TermScore
olanzapine0.400000
LOWER IN olanzapine0.285714
LOWER IN diet0.222222
c57bl/6j0.153846
high fat diet0.121212
LOWER IN high fat diet0.100000
female organism0.100000
diet0.074074
mus musculus0.027027
LOWER IN control0.008929
control0.008795
united states of america0.006645
feces0.004577
Fraction of dbbact annotations with this term covered by the query
TermScore
LOWER IN olanzapine1.000000
olanzapine0.500000
LOWER IN diet0.333333
c57bl/6j0.083333
LOWER IN high fat diet0.071429
high fat diet0.066667
female organism0.052632
diet0.041667
mus musculus0.013699
LOWER IN control0.004545
control0.004444
united states of america0.003333
feces0.002294
Fraction of annotations for the query sequences containing the term
TermScore
female organism1.000000
united states of america1.000000
chapel hill1.000000
laboratory housing1.000000
feces1.000000
mus musculus1.000000
c57bl/6j1.000000
high fat diet0.666667
control0.416667
placebo0.416667
diet0.333333
pre-high-fat diet0.333333
olanzapine0.333333
LOWER IN control0.250000
LOWER IN placebo0.250000
LOWER IN olanzapine0.166667
LOWER IN high fat diet0.166667
LOWER IN diet0.166667
LOWER IN pre-high-fat diet0.166667
Number of experiments associating the term to the sequence
TermScore
diet1.000000
pre-high-fat diet1.000000
LOWER IN olanzapine1.000000
LOWER IN control1.000000
LOWER IN placebo1.000000
LOWER IN high fat diet1.000000
female organism1.000000
united states of america1.000000
chapel hill1.000000
laboratory housing1.000000
feces1.000000
mus musculus1.000000
c57bl/6j1.000000
olanzapine1.000000
control1.000000
placebo1.000000
high fat diet1.000000
LOWER IN diet1.000000
LOWER IN pre-high-fat diet1.000000
Exp. ID User ID Description Date Region Sequences Status Flag
2354gpt-5Baseline mouse fecal samples (regular chow, pre-HFD) (dominant diet, female organism, united states of america, chapel hill, laboratory housing, feces, mus musculus, pre-high-fat diet, c57bl/6j)2026-03-05v41 / 12pendingNo
2354gpt-5Olanzapine-treated mouse fecal samples (high-fat diet) (dominant female organism, high fat diet, united states of america, chapel hill, laboratory housing, olanzapine, feces, mus musculus, c57bl/6j)2026-03-05v41 / 20pendingNo
2354gpt-5Placebo (no drug) mouse fecal samples (high-fat diet) (dominant female organism, high fat diet, control, united states of america, chapel hill, placebo, laboratory housing, feces, mus musculus, c57bl/6j)2026-03-05v41 / 24pendingNo
2354gpt-5Effect of olanzapine on gut microbiome under high-fat diet ( high in olanzapine compared to control placebo in female organism high fat diet united states of america chapel hill laboratory housing feces mus musculus c57bl/6j )2026-03-05v41 / 34pendingNo
2354gpt-5Effect of olanzapine on gut microbiome under high-fat diet ( high in control placebo compared to olanzapine in female organism high fat diet united states of america chapel hill laboratory housing feces mus musculus c57bl/6j )2026-03-05v41 / 65pendingNo
2354gpt-5Olanzapine-treated mouse fecal samples (high-fat diet) (common female organism, high fat diet, united states of america, chapel hill, laboratory housing, olanzapine, feces, mus musculus, c57bl/6j)2026-03-05v41 / 147pendingNo
2354gpt-5Placebo (no drug) mouse fecal samples (high-fat diet) (common female organism, high fat diet, control, united states of america, chapel hill, placebo, laboratory housing, feces, mus musculus, c57bl/6j)2026-03-05v41 / 155pendingNo
2354gpt-5Baseline mouse fecal samples (regular chow, pre-HFD) (common diet, female organism, united states of america, chapel hill, laboratory housing, feces, mus musculus, pre-high-fat diet, c57bl/6j)2026-03-05v41 / 192pendingNo
2354gpt-5High-fat diet impact on gut microbiome (diet shift from regular chow) ( high in control placebo high fat diet compared to diet pre-high-fat diet in female organism united states of america chapel hill laboratory housing feces mus musculus c57bl/6j )2026-03-05v41 / 197pendingNo
2354gpt-5Combined high-fat diet exposure vs baseline chow ( high in olanzapine control placebo high fat diet compared to diet pre-high-fat diet in female organism united states of america chapel hill laboratory housing feces mus musculus c57bl/6j )2026-03-05v41 / 204pendingNo
2354gpt-5High-fat diet impact on gut microbiome (diet shift from regular chow) ( high in diet pre-high-fat diet compared to control placebo high fat diet in female organism united states of america chapel hill laboratory housing feces mus musculus c57bl/6j )2026-03-05v41 / 251pendingNo
2354gpt-5Combined high-fat diet exposure vs baseline chow ( high in diet pre-high-fat diet compared to olanzapine control placebo high fat diet in female organism united states of america chapel hill laboratory housing feces mus musculus c57bl/6j )2026-03-05v41 / 262pendingNo

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